David Harbour and John Cena are set to star in The Family Disappears, a new comedy drama that dives into the chaos of a father’s unraveling world. The film centers on a man overwhelmed by work, who returns from a business trip only to discover his entire family has vanished without a trace. In their place: a stranger who has bought the house and moved in, claiming it as their own. There’s no note. No call. Just silence and a front door left ajar. The script, an original story by Brendan O’Hare — known for Eggland and The New Yorker Presents, is being directed by Jonathon Etzler, whose previous work includes Bad Apples and One More Time. Fifth Season is producing the project, with Nick Weidenfeld and Alexis Garcia overseeing production. Shooting begins November 10 in Atlanta, Georgia. Harbour, a multi-time Emmy winner for HBO’s DTF St Louis, has a packed slate this year. He’s already lined up for Evil Genius, Violent Night 2, Little One, and Avengers: Doomsday, where he reprises his role as the Red Guardian. First introduced in Thunderbolts. He’ll also reunite with Millie Bobby Brown, his on-screen daughter from Stranger Things, in a spy series written by Jack Thorne, the mind behind Enola Holmes. Cena, meanwhile, just earned his first-ever Emmy nomination as executive producer of Heads of State, a Prime Video action-comedy film. He recently appeared in Coyote vs Acme and Little Brother, and has two more films in post-production: Matchbox: The Movie and One Attempt Remaining. The film’s genre remains unconfirmed, whether it leans into dark humor, suspense, or something more surreal. But the premise alone promises tension. With Harbour and Cena at the helm, and a director known for sharp character-driven stories, The Family Disappears could be one of the year’s most talked-about releases. The question isn’t if it’ll generate buzz, it’s how long before someone starts checking their own front door.